الأبحاث والكتب المنشورة

Alhaddad H, Cisternino S, Declèves X, Tournier N, Schlatter J, Chiadmi F, Risède P, Smirnova M, Besengez C, Scherrmann JM, Baud FJ, Mégarbane B. Respiratory toxicity of buprenorphine results from the blockage of P-glycoprotein-mediated efflux of norbuprenorphine at the blood-brain barrier in mice. Crit Care Med 2012. (IF : 6,33)

Mégarbane B, Alhaddad H, Declèves X. Reduced pupil diameter in volunteers on stable buprenorphine maintenance therapy with telaprevir: a drug-drug interaction involving p-glycoprotein at the blood-brain barrier? Antimicrob Agents Chemother. 2012 Nov;56(11):6070. (IF: 4,84)

Mégarbane B, Alhaddad H. P-glycoprotein should be considered as an additional factor contributing to opioid-induced respiratory depression in paediatrics: the buprenorphine example. Br J Anaesth. 2013 May;110(5):842.(IF: 4,24)

Mégarbane B, Alhaddad H. Can P-glycoprotein expression on malignant tumortissues predict opioid transport at the blood-brain barrier in cancer patients?Pharmacol Rep. 2013;65(1):235-6.. (IF: 1,97)

Alhaddad H, Cisternino S, Saubamea B, Schlatter J, Chiadmi F, Risède P,Smirnova M, Cochois-Guégan V, Tournier N, Baud FJ, Mégarbane B. Gender and strain contributions to the variability of buprenorphine-related respiratory toxicity inmice. Toxicology. 2013 Mar 8;305:99-108.(IF: 3,76)

Mohammed W, Alhaddad H, Marie N, Tardy F, Lamballais F, Risède P, Noble F Baud FJ, Mégarbane B. Comparison of tolerance to morphine-induced respiratory and analgesic effects in mice. Toxicol Lett. 2013 Mar 13;217(3):251-9.(IF: 3,76)